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CoV-2 N (127 a.a.)

CoV-2 N (127 a.a.)

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  • CoV-2 N (127 a.a.)

  • Coronavirus 2019 Nucleocapsid (127 a.a.), Recombinant
  • SARS-043
  • Shipped with Ice Packs

Catalogue number

SARS-043

Introduction

A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.

The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2)  in humans.

While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.

Description

The E.Coli derived recombinant protein contains the Coronavirus 2019 C-terminal region 127 a.a. from the Nucleocapsid protein and fused to GST-6xHis tag at N-terminal and having a Mw. of 39.4 kDa.

Source

E.Coli.

Purification Method

NTA Sepharose-Affinity Purification.

Physical Appearance

Sterile Filtered clear solution.

Formulation

CoV-2 Nucleocapsid protein solution is supplied in 50mM Tris-HCl pH 8, 1M Urea, and 50% Glycerol.

Stability

CoV-2 Spike Protein is shipped on ice packs. Upon arrival, Store at -20°C.

Purity

CoV-2 Nucleocapsid protein is >95% pure as determined SDS-PAGE.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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