SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
The HEK293 derived recombinant protein contains the SARS Coronavirus Nucleoprotein, amino acids 2-422 fused to His tag at C-terminal.
Purified by immobilized metal affinity chromatographic technique.
SARS Nucleocapsid protein solution is supplied in 0.2M NaCl & 50mM HEPES pH-8.
SARS nucleoprotein is shipped on ice packs. Upon arrival, Store at -20°C.
Protein is >85% pure as determined SDS-PAGE.