CD8A, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, MAL, CD8, Leu2, p32, T-cell surface glycoprotein CD8 alpha chain isoform 1.
CD8 protein is a glycoprotein that is located on the cell surface of cytotoxic T lymphocytes the interferes interactions between cells of the immune system. This protein is a coreceptor that helps detect antigens shown by the APC (antigen presenting cells) as part of the class I MHC proteins. It can be a homodimer build from 2 alpha chains orheterodimer build from alpha and beta chains.
CD8A Human Recombinant produced in Baculovirus is a single, glycosylated, polypeptide chain containing 170 amino acids (22-182aa) and having a molecular mass of 18.7kDa.
CD8A is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
The CD8A solution (0.5mg/ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
ADPSQFRVSP LDRTWNLGET VELKCQVLLS NPTSGCSWLF QPRGAAASPT FLLYLSQNKP
KAAEGLDTQR FSGKRLGDTF VLTLSDFRRE NEGYYFCSAL SNSIMYFSHF VPVFLPAKPT
TTPAPRPPTP APTIASQPLS LRPEACRPAA GGAVHTRGLD FACDHHHHHH
Safety Data Sheet
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.