prospec

CD86 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • CD86 Human
  • CD86 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2620

Synonyms

B7-2/CD86, CD86, B7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1.

Introduction

CD86, also known as B7-2 or Cluster of Differentiation 86 is a protein necessary for T cell activation and survival, it is expressed on cells that are antigen-presenting cells and acts as costimulatory signals for T cells. CD86 is the ligand for CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation), two different proteins.

Description

CD86 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 223 amino acids (31-247a.a.) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CD86 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD86 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by SDS-PAGE.

Amino acid sequence

YFNETADLPC QFANSQNQSL SELVVFWQDQ ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ PPPDHIPHHH HHH.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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