prospec

CD62E Antibody

  • Name
  • Description
  • Pricings
  • Quantity
  • CD62E Antibody
  • E-Selectin, Mouse Anti-Human
  • Shipped at Room temp.

Catalogue number

ANT-237

Synonyms

E-selectin, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, CD62E antigen, SELE, ELAM1, ELAM, ESEL, CD62E.

Type

Mouse Anti Human Monoclonal.

Introduction

E-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. CD62E is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. CD62E is found in cytokine-stimulated endothelial cells and is accountable for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It demonstrates structural features such as the existence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. E-Selectin participates in the interaction between leukocytes and the endothelium and appears to be involved in the pathogenesis of atherosclerosis.

Clone

hCD62E.

Immunogen

Purified, Activated T-Cells.

Ig Subclass

Mouse IgG1.

Purification Method

Ion exchange column.

Formulation

1mg/ml in PBS (after reconstitution).

Storage Procedures

Lyophilized: store at 4 C. After reconstitution, if not intended for use within a month, aliquot and store at -20 C.

Solubility

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Applications

Staining antibody. For staining, use 10µl/1,000,000 cells.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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