prospec

CD40 Antibody, FITC

  • Name
  • Description
  • Pricings
  • Quantity
  • CD40 Antibody, FITC
  • CD40, Mouse Anti-Human, FITC
  • Shipped at Room temp.

Catalogue number

ANT-265

Synonyms

p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

Type

Mouse Anti Human Monoclonal.

Introduction

CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

Clone

hCD40.

Immunogen

Activated Human B cells.

Ig Subclass

Mouse IgG1.

Purification Method

Protein-A.

Formulation

1mg/ml in PBS (after reconstitution).

Storage Procedures

Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Solubility

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Applications

Staining antibody. For staining, use 10µl/1,000,000 cells.

Available Conjugates

This antibody is also available unconjugated and conjugated to Biotin. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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