prospec

CD200R1 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • CD200R1 Human
  • CD200 Receptor 1 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2548

Synonyms

Cell surface glycoprotein CD200 receptor 1 isoform d, CD200R1, CD200R, HCRTR2, MOX2R, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, Cd200r1, Mox2r, Ox2r.

Introduction

CD200R1, also known as cell surface glycoprotein CD200 receptor 1, is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 inhibitory signaling pathway has been involved in taking a prominent role in limiting inflammation in a broad range of inflammatory diseases. CD200R1 signaling inhibits the expression of proinflammatory molecules including tumor necrosis factor, interferons, in addition to inducible nitric oxide synthase in response to selected stimuli.

Description

CD200R1 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 462 amino acids (24-243 a.a.) and having a molecular mass of 51.9kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). CD200R1 is expressed with 242 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD200R1 protein solution (0.25mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADLSSSLCMD EKQITQNYSK VLAEVNTSWP VKMATNAVLC CPPIALRNLI IITWEIILRG QPSCTKAYKK ETNETKETNC TDERITWVSR PDQNSDLQIR TVAITHDGYY RCIMVTPDGN FHRGYHLQVL VTPEVTLFQN RNRTAVCKAV AGKPAAHISW IPEGDCATKQ EYWSNGTVTV KSTCHWEVHN VSTVTCHVSH LTGNKSLYIE LLPVPGAKKS AKLLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.

Back to Top