prospec

C6ORF108 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • C6ORF108 Human
  • Chromosome 6 Open Reading Frame 108 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-249

Synonyms

c-Myc-responsive protein Rcl, RCL,putative c-Myc-responsive.

Introduction

C6ORF108 is stimulated by c-Myc protein that is a transcription factor that is involved in the regulation of cell proliferation, differentiation, and apoptosis. C6ORF108 functions in rat in cellular proliferation and c-Myc-mediated transformation. C6ORF108 catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5''-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5''-monophosphates comprising purine bases are favored to those comprising of pyrimidine bases.

Description

C6ORF108 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 194 amino acids (1-174 a.a.) and having a molecular mass of 21.2kDa.
C6ORF108 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

The C6ORF108 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH-8), 1mM DTT, and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MAAAMVPGRS ESWERGEPGR PALYFCGSIR GGREDRTLYE RIVSRLRRFG TVLTEHVAAA ELGARGEEAA
GGDRLIHEQD LEWLQQADVV VAEVTQPSLG VGYELGRAVA FNKRILCLFR PQSGRVLSAM IRGAADGSRF QVWDYEEGEV EALLDRYFEA
DPPGQVAASP DPTT.

Safety Data Sheet

Usage

ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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