GI24, Platelet receptor Gi24, VSIR, V-Set Immunoregulatory Receptor, SISP1, GI-24, B7-H5, Stress Induced Secreted Protein 1. VISTA.
Chromosome 10 Open Reading Frame 54, also known as C10ORF54 is part of
the immunoglobulin superfamily. Like a transmembrane molecule, C10ORF54 is
expressed in the bone on embryonic stem cells (ESCs), and on tumor cell surface as well. Accordingly, C10ORF54 supports the differentiation of
ESC and ehhances BMP4 induced signaling in ESC, however C10ORF54 is also down
regulated following to BMP4 exposure.
C10ORF54 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 167 amino acids (33-191a.a.) and having a molecular mass of 18.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).
C10ORF54 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
filtered colorless solution.
protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
TCRILGPVSK GHDVTIYKTW YLSSRGEVQM CKEHRPIRNF TLQHLQHHGS HLKANASHDQ PQKHGLELAS
DHHGNFSITL RNVTPRDSGL YCCLVIELKN HHPEQRFYGS MELQVQAGKG SGSTCMASNE QDSDSITAAL
Safety Data Sheet
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.