- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2073
Synonyms
B9 Protein Domain 1, MKSR1, Endothelial Precursor Protein
B9, MKS1-Related Protein 1, MKS9, B9 Domain-Containing Protein 1, EPPB9, B9, B9
domain-containing protein 1.
Introduction
B9 domain-containing protein (B9D1) is one of the numerous proteins
which take part in ciliogenesis. Alterations in expression of B9D1 have been found
in a family with Meckel syndrome. The Meckel syndrome has been associated with
at least six different genes. B9D1 is placed within the Smith-Magenis syndrome
region on chromosome 17. Three alternatively spliced transcript variants which encode
dissimilar proteins have been found for B9D1.
Description
B9D1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and
having a molecular mass of 25.2kDa.
B9D1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
B9D1 protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMATASPS VFLLMVNGQV ESAQFPEYDD LYCKYCFVYG QDWAPTAGLE
EGISQITSKS QDVRQALVWN FPIDVTFKST NPYGWPQIVL SVYGPDVFGN DVVRGYGAVH VPFSPGRHKR
TIPMFVPEST SKLQKFTSWF MGRRPEYTDP KVVAQGEGRE
VTRVRSQGFV TLLFNVVTKD MRKLGYDTGP SDTQGVLGPS PPQSFPQ.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.