prospec

AMIGO2 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • AMIGO2 Human
  • Adhesion Molecule with Ig-Like Domain 2 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2254

Synonyms

Adhesion Molecule with Ig-Like Domain 2, Differentially Expressed in Gastric, Adenocarcinomas, AMIGO-2, ALI1, DEGA, Differentially Expressed in Gastric, Adenocarcinoma, Amphoterin-Induced Gene and Open Reading Frame 2, Transmembrane Protein AMIGO2, Amphoterin Induced Gene, Alivin 1, Alivin-1.

Introduction

Adhesion Molecule with Ig-Like Domain 2, also known as AMIGO2 is a member of the leucine-rich repeat family. AMIGO2 arbitrates homophilic in addition to heterophilic cell-cell interaction with AMIGO1 or AMIGO3. Furthermore, AMIGO2 contributes to signal transduction via its intracellular domain and is also essential for tumorigenesis of a subset of gastric adenocarcinomas.

Description

AMIGO2 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 367 amino acids (40-398a.a.) and having a molecular mass of 41.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).
AMIGO2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Insect cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

AMIGO2 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Amino acid sequence

VCPTACICAT DIVSCTNKNL SKVPGNLFRL IKRLDLSYNR IGLLDSEWIP VSFAKLNTLI
LRHNNITSIS TGSFSTTPNL KCLDLSSNKL KTVKNAVFQE LKVLEVLLLY NNHISYLDPS AFGGLSQLQK LYLSGNFLTQ FPMDLYVGRF KLAELMFLDV SYNRIPSMPM HHINLVPGKQ LRGIYLHGNP FVCDCSLYSL LVFWYRRHFS SVMDFKNDYT CRLWSDSRHS RQVLLLQDSF MNCSDSIING SFRALGFIHE AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR SHAHEAFNTL EHHHHHH.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Back to Top