Anterior gradient protein 2 homolog, Secreted cement gland protein XAG-2 homolog, AG-2, hAG-2, HPC8, AGR2, AG2, GOB-4, HAG-2, XAG-2.
AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.
AGR2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids (21-175 a.a.) and having a molecular mass of 21.9 kDa. AGR2 protein is fused to a 36 amino acid His-Tag at N-terminus and purified by standard chromatography.
Sterile filtered colorless solution.
The protein contains 20mM Tris-HCl pH 8.0, 1mM DTT, 1mM EDTA and 10% Glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL.
Safety Data Sheet
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