prospec

IGF-IR Human

  • Name
  • Description
  • Pricings
  • Quantity
  • IGF-IR Human
  • Insulin-like Growth Factor-1 Receptor Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PKA-237

Synonyms

Insulin-like growth factor 1 receptor, EC 2.7.10.1, Insulin-like growth factor I receptor, IGF-I receptor, CD221 antigen, CD221, IGFIR, JTK13, MGC18216, MGC142170, MGC142172.

Introduction

The Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembranereceptorthat is activated by IGF-1and by the related growth factor IGF-II. It belongs to the large class of tyrosine kinasereceptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscleand other target tissues.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and Beta-subunits, which are disulfide-linked in a Beta-alpha-alpha-Beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the Beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Description

Insulin-like growth factor 1 receptor Human Recombinant encoding 1213-1367 amino acids expressed in E.coli, shows a 43kDa band on SDS-PAGE (Including GST tag).
IGF-IR is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile filtered liquid.

Formulation

IGF-IR protein in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.

Stability

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please avoid freeze-thaw cycles.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Back to Top