prospec

Atosiban

  • Name
  • Description
  • Pricings
  • Quantity
  • Atosiban
  • Atosiban
  • Shipped at Room temp.

Catalogue number

HOR-239

Introduction

Atosiban is the first oxytocin antagonist to be specifically developed for the treatment of preterm labor. Atosiban has a specific mode of action, inhibiting oxytocin-induced uterine contractions by blocking oxytocin receptors in the uterus. Extensive clinical investigations have shown Atosiban to be at least as effective as current tocolytic agents. In addition, due to its novel and specific mode of action, Atosiban has a markedly improved maternal side effects profile compared with conventional therapies.

Description

Atosiban also called ADH (Anti-Diuretic Hormone) has a molecular formula of C43H67N11O12S2, C[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2 having a Mw of 994.2 Dalton.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

The Atosiban peptide was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized Atosiban in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Atosiban although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Atosiban should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity

Greater than 99.0% as determined by analysis by RP-HPLC.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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