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SARS Nucleocapsid PT3851

SARS Nucleocapsid PT3851

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • SARS Nucleocapsid PT3851

  • Mouse Anti SARS Nucleocapsid Clone PT3851
  • ANT-763
  • Shipped with Ice Packs

Catalogue number

ANT-763

Type

Mouse antibody Monoclonal.

Introduction

SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.

Description

SARS Nucleoprotein antibody clone PT3851 is specific for the nucleocapsid  SARS-CoV protein and recognizes the nucleoprotein of SARS-CoV-2 by ELISA.

Isotype

Mouse IgG2b.

Clone

PT3851

Formulation

1mg/ml in PBS and 0.09% NaN3.

Physical Appearance

Sterile Filtered liquid formulation.

Immunogen

Recombinant protein fragment 1-49 a.a. of the SARS nucleoprotein.

Applications

ELISA.

Purity

Greater than 90% as determined by SDS-PAGE gel.

Purification Method

Protein A affinity purified.

Stability

Store at 4°C, stable for 2 weeks. For long-term storage, store at -20°C.

Safety Data Sheet

Usage

Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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