c-myc Antibody
c-myc, Mouse anti Human

Synonyms:
MYC, CMYC, C-MYS, V-MYC, P64

Type:
Mouse Anti Human Monoclonal

Introduction:
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Clone:
NYRhc-myc

Ig Subclass:
mouse IgG1

Purification Method:
Protein A

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Antibody is shipped lyophilized at ambient temperature.

Storage Procedures:
In lyophilized form, for long periods, store at 4^oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20^oC.

Reconstitution:
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4^oC.

Titer:
By Western blot 1:2,000 dilution will yield a strong band in WB.

Additional Information:
This antibody was produced in BALB/c mice

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.