c-myc Antibody | ProSpec

Description

Our Price

Quantity

Shipping

c-myc, Mouse anti Human

	500µg($155)
	1mg($290)
	($0)

Catalogue Number

ANT-211

Synonyms

MYC, CMYC, C-MYS, V-MYC, P64.

Type

Mouse Anti Human Monoclonal.

Introduction

c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Clone

NYRhc-myc.

Immunogen

synthetic peptides.

Ig Subclass

mouse IgG1.

Purification Method

Protein A.

Protein concentration

1mg/ml in PBS (after reconstitution).

Storage Procedures

Antibody is shipped lyophilized at ambient temperature.

Reconstitution

Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC.

Titer

By Western blot 1:2,000 dilution will yield a strong band in WB.

Additional Information

This antibody was produced in BALB/c mice UsageProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.