Vietnam 1203/04 | Influenza A Virus

Description

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H5N1 Influenza-A Virus Vietnam 1203/04 Recombinant

	2µg($50)
	10µg($200)
	100µg($1800)

Ice Packs

Catalogue Number

IHA-010

Introduction

Influenza A virus subtype H5N1 is a subtype of the Influenza A virus. Subtype H5N1 is commonly known as avian influenza or bird flu. H5N1 may cause more than one influenza pandemicas it is expected to continue mutating in birds. The dominant strain of HPAI A (H5N1) evolved creating the Z genotype. It has also been called Asian lineage HPAI/A/H5N1 which is divided into 2 antigenic clades. "Clade 1 includes human and bird isolates from Vietnam, Thailand, and Cambodia and bird isolates from Laosand Malaysia. Clade 2 viruses were first identified in bird isolates from China, Indonesia, Japan, and South Korea before spreading westward to the Middle East, Europe, and Africa.

Description

Recombinant Full-Length H5N1 A/Vietnam/1203/04 is glycosylated with N-linked sugars, produced using baculovirus and when processed under denaturing conditions splits into the HA1 and HA2 domains which are approximately 45,000 and 25,000 Daltons respectively H5N1 A/Vietnam/1203/04 accession number is ISDN38687.

Source

Baculovirus Insect Cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The Recombinant H5N1 A/Vietnam/1203/04 solution contains 10mM Sodium Phosphate, pH 7.1, 0.005% Tween-20 and 150mM NaCl.

Stability

H5N1 A/Vietnam/1203/04 Recombinant should be stored at 4°C.

Immunological Activity

Western-Blot 0.1µg -1µg per strip, ELISA 1µg/Well.

Purity

Greater than 90.0% as determined byAnalysis by SDS-PAGE, HA1 and HA2 bands are observed using SDS-PAGE under reducing conditions.

Amino Acid Sequence

V K M E K I V L L F A I V S L V K S D Q I C I G Y H A N N S T E Q V D T I M E
K N V T V T H A Q D I L E K K H N G K L C D L D G V K P L I L R D C S V A G
W L L G N P M C D E F I N V P E W S Y I V E K A N P V N D L C Y P G D F N D
Y E E L K H L L S R I N H F E K I Q I I P K S S W S S H E A S L G V S S A C P
Y Q G K S S F F R N V V W L I K K N S T Y P T I K R S Y N N T N Q E D L L V
L W G I H H P N D A A E Q T K L Y Q N P T T Y I S V G T S T L N Q R L V P R I
A T R S K V N G Q S G R M E F F W T I L K P N D A I N F E S N G N F I A P E
Y A Y K I V K K G D S T I M K S E L E Y G N C N T K C Q T P M G A I N S S M
P F H N I H P L T I G E C P K Y V K S N R L V L A T G L R N S P Q R E R R R
K K R G L F G A I A G F I E G G W Q G M V D G W Y G Y H H S N E Q G S G
Y A A D K E S T Q K A I D G V T N K V N S I I D K M N T Q F E A V G R E F N
N L E R R I E N L N K K M E D G F L D V W T Y N A E L L V L M E N E R T L D
F H D S N V K N L Y D K V R L Q L R D N A K E L G N G C F E F Y H K C D N
E C M E S V R N G T Y D Y P Q Y S E E A R L K R E E I S G V K L E S I G I Y
Q I L S I Y S T V A S S L A L A I M V A G L S L W M C S N G S L Q C R I C I.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.