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Catalogue Number
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ENZ-512
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Synonyms
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SULT2B1, HSST2, EC 2.8.2.2, Sulfotransferase 2B1, Hydroxysteroid sulfotransferase 2, ST2B1, Sulfotransferase family cytosolic 2B member 1.
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Introduction
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SULT2B1 catalyzes the sulfate conjugation of numerous hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation enhances the water solubility of molecules, and therefore their renal excretion, however it can also result in bioactivation to form active metabolites. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and participates in cholesterol sulfation in human skin.
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Description
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SULT2B1 Human Recombinant produced in E.Coli is a single, non-glycosylated,
polypeptide chain containing 365 amino acids (1-365 a.a.) and having a molecular mass of 41.3 kDa. SULT2B1 protein is purified by standard chromatography.
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Source
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Escherichia Coli.
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Physical Appearance
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Sterile filtered colorless solution.
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Formulation
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(SULT2B1 Human solution containing 20mM Trsi HCL pH-7.5, & 10% glycerol.
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Stability
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SULT2B1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
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Amino acid sequence
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MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS
WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL
KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS.
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Purity
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Greater than 85% as determined by SDS-PAGE.
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Usage
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ProSpec''s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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