PSMG3 Human | ProSpec

Description

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Quantity

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Proteasome Assembly Chaperone 3 Human Recombinant

	1µg($50)
	5µg($130)
	50µg($1100)

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Catalogue Number

PRO-261

Synonyms

Proteasome assembly chaperone 3, PAC-3, hPAC3, PSMG3, PAC3, C7orf48, MGC10911.

Introduction

PSMG3 is a chaperone protein that promotes assembly of the 20S proteasome. PSMG3 may cooperate with PSMG1-PSMG2 heterodimers to coordinate the correct assembly of proteasomes. PSMG3 interacts with PSMG4, as well as directly with alpha and beta subunits of the 20S proteasome but dissociates prior to the formation of half-proteasomes, probably upon recruitment of POMP.

Description

PSMG3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 142 amino acids (1-122 a.a.) and having a molecular mass of 15.2kDa. The PSMG3 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The PSMG3 solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 10% Glycerol.

Stability

PSMG3 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.