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Protein Catalog >> Monoclonal Antibodies >> Other >> MOG Antibody
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Description
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myelin oligodendrocyte glycoprotein, Mouse Antibody
 
Catalogue Number ANT-199
Synonyms MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN.
Type Mouse Antibody Monoclonal.
Introduction MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication.
Clone NYRMOG.
Immunogen synthetic pMOG 35-55.
Ig Subclass mouse IgG1.
Purification Method Ion exchange column.
Protein concentration 1mg/ml in PBS (after reconstitution).
Shipping Conditions Antibody is shipped lyophilized at ambient temperature.
Storage Procedures In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Reconstitution Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC.
Titer By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Applications Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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