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Products catalog >> Monoclonal Antibodies >> Anti Mouse Cytokine >> IL-2 Antibody

IL-2 Antibody
Interleukin-2, Rat Anti-Mouse

Catalog No. ANT-105
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Synonyms:
T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.

Type:
Rat Anti Mouse Monoclonal

Introduction:
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Clone:
NYRmIL-2

Immunogen:

r.Murine IL-2

Ig Subclass:
Rat IgG2a

Purification Method:
Ion exchange

Protein concentration:
1mg/ml in PBS (after reconstitution)

Shipping Conditions:
Antibody is shipped lyophilized at ambient temperature.

Storage Procedures:
In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitution:
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4oC.

Titer:
Not tested by ELISA. 1:1,000 dilution will block T cell proliferation induced by specific Ag or concanavaline A.

Usage:
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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