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Insulin decreases blood glucose concentration. it increases cell permeability to monosaccharides, amino acids and fatty acids. it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Insulin Bovine is a two chain, glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5733 Dalton. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Insulin Bovine is purified by proprietary chromatographic techniques.
Bovine Pancreas
Sterile Filtered White lyophilized (freeze-dried) powder.
The Insulin Bovine was lyophilized from a concentrated (1mg/ml) solution with no additives.
It is recommended to reconstitute the lyophilized Insulin Bovine in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Lyophilized Insulin Bovine although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Insulin Bovine should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
26 units/mg.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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