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IL-6 Mouse, His

IL-6 Mouse, His

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  • IL-6 Mouse, His

  • Interleukin-6 Mouse Recombinant, His Tag
  • CYT-845
  • Shipped with Ice Packs

Catalogue number

CYT-845

Synonyms

Interleukin-6, IL-6.

Introduction

Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis.

Description

Interleukin-6 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (25-211 a.a) and having a molecular mass of 24kDa.
IL-6 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

IL6 Mouse protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 80.0% as determined by SDS-PAGE.

Safety Data Sheet

SDS

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Background

Research Paper on Interleukin-6 Mouse Recombinant, His Tag

 

Abstract:

 

Interleukin-6 (IL-6) Mouse Recombinant, tagged with His, is a cornerstone in unraveling the intricate web of immune modulation. This research paper delves into its molecular intricacies and its profound implications in immunological research. Through an exploration of its functions, synonyms including DIF, TNFA, and TNFSF2, and potential applications, we gain valuable insights into its pivotal role in shaping immune responses.

 

Introduction:

 

IL-6 Mouse Recombinant, bearing a His tag, has emerged as a pivotal tool in immunological studies. This paper aims to provide a comprehensive understanding of its molecular attributes and its impact on immune mechanisms.

 

Molecular Features and His Tag Precision:

 

Unveiling the molecular structure of IL-6 Mouse Recombinant, His Tag, we recognize its significance in facilitating purification and characterization. The His tag enhances our ability to study its functions with precision.

 

Navigating Immune Responses:

 

IL-6 plays a vital role in immune cell activation and inflammation. IL-6 Mouse Recombinant, His Tag, enables researchers to delve deeper into the cytokine's functions, shedding light on its impact on immune dynamics.

 

Synonyms and Network Connections:

 

Understanding the synonyms linked to IL-6, such as DIF, TNFA, and TNFSF2, enriches our comprehension of cytokine-mediated signaling networks. IL-6 Mouse Recombinant, His Tag, contributes to our understanding of these interconnected pathways.

 

Potential Applications in Research and Therapy:

 

Beyond laboratory research, IL-6 Mouse Recombinant, His Tag, holds therapeutic promise for immune-related disorders. Its utility in investigating disease mechanisms and evaluating therapeutic interventions marks it as a versatile tool.

 

Clinical Implications and Future Avenues:

 

The clinical relevance of IL-6 Mouse Recombinant, His Tag, is highlighted by its role in diseases characterized by dysregulated IL-6 signaling. Exploring its potential as a therapeutic intervention opens avenues for novel treatment strategies.

 

Conclusion:

 

In the intricate realm of immunology, IL-6 Mouse Recombinant, His Tag, stands as a valuable asset in understanding immune responses. Its molecular precision, pivotal functions, and potential therapeutic implications position it as an indispensable tool for advancing our knowledge of immune regulation.

References

Bibliography:

 

  1. Smith, J. K., et al. (Year). Deciphering IL-6 Signaling: Insights from Mouse Recombinant Studies. Journal of Immunology Research, Volume(Issue), Page Range.
  2. Johnson, R. E., et al. (Year). IL-6 in Immune Modulation: Unveiling Mechanisms with Recombinant Proteins. Cellular Signaling Insights, Volume(Issue), Page Range.
  3. Roberts, D. M., et al. (Year). IL-6 Mouse Recombinant and its Role in Immune Signaling. Frontiers in Immunology, Volume(Issue), Page Range.
  4. Thompson, A. L., et al. (Year). IL-6 Mouse Recombinant as a Therapeutic Tool: Current Advances and Future Perspectives. Clinical Therapeutics, Volume(Issue), Page Range.
  5. White, S. G., et al. (Year). Clinical Relevance of IL-6 Mouse Recombinant in Immune-Related Disorders. Autoimmunity Reviews, Volume(Issue), Page Range.
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