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Protein Catalog >> Monoclonal Antibodies >> Anti Human Cytokine >> IL 1RA Antibody
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Description
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Interleukin-1 Receptor Anatagonist, Mouse Anti-Human
 
Catalogue Number ANT-238
Synonyms IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430.
Type Mouse Anti Human Monoclonal.
Introduction Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Clone NYR-hIL1RA.
Immunogen r.Human IL-1RA.
Ig Subclass Mouse IgG2b.
Purification Method Ion exchange.
Protein concentration 1mg/ml in PBS (after reconstitution).
Shipping Conditions Antibody is shipped lyophilized at ambient temperature.
Storage Procedures In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Reconstitution Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC.
Applications Direct ELISA, Western Blot, Immuneprecipitation.
Titer By direct ELISA, 1:10,000 dilution will yield 0.8 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
» IL 1RA Human
» IL 1RA Human His
» IL 1RA Mouse
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