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Catalogue Number
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ANT-238
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Synonyms
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IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430.
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Type
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Mouse Anti Human Monoclonal.
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Introduction
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Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Clone
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NYR-hIL1RA.
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Immunogen
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r.Human IL-1RA.
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Ig Subclass
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Mouse IgG2b.
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Purification Method
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Ion exchange.
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Protein concentration
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1mg/ml in PBS (after reconstitution).
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Shipping Conditions
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Antibody is shipped lyophilized at ambient temperature.
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Storage Procedures
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In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
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Reconstitution
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Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC.
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Applications
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Direct ELISA, Western Blot, Immuneprecipitation.
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Titer
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By direct ELISA, 1:10,000 dilution will yield 0.8 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
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Usage
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Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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| Contact Us |
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Toll Free Phone: 1-(866)-245-0885 Toll Free Fax: 1-(866)-796-4944 Postal Address: PO Box 6591, East Brunswick, 08816 NJ |
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Toll Free Phone: 00-800-800-66666 Toll Free Fax: 00-800-800-67890 |
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International Phone: +972-8-9471175 International Fax: +972-8-9460534 Postal Address: PO Box 4157, Ness-Ziona, 74140 Israel
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Website : www.prospecbio.com Email: info@prospecbio.com |
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