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Catalogue Number
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CYT-550
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Synonyms
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Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956.
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Introduction
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Interferon-beta 1b has antiviral, antibacterial and anticancer activities.
Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.
Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.
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Description
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Interferon beta Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 162 amino acids and having a molecular mass of 19.8 kDa.
Mouse IFN beta is purified by proprietary chromatographic techniques.
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Source
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Escherichia Coli.
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Formulation
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IFN-b Mouse solution containing 10mM sodium phosphate pH-7.5 and 0.5M ammonium sulfate.
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Stability
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Store the IFN-beta at 4°C for 4 weeks.
Do not freeze/thaw.
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Purity
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Greater than 90.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
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Biological Activity
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Determined in a viral cytopathic effect inhibition assay.
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Amino acid sequence
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MINYKQLQLQERTNIRKCQELLEQLNGKINLTYRADFKIPMEMTEKMQKS
YTAFAIQEMLQNVFLVFRNNFSSTGWNETIVVRLLDELHQQTVFLKTVLE
EKQEERLTWEMSSTALHLKSYYWRVQRYLKLMKYNSYAWMVVRAEIFR
NFLIIRRLTRNFQN.
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Usage
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ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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| Contact Us |
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Website : www.prospecbio.com
Email: info@prospecbio.com |
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Rehovot , 76103, Israel |
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