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Protein Catalog >> Viral Antigens >> Hepatitis D >> HDV
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Description
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Hepatitis D Virus Recombinant
Ice Packs
Catalogue Number HDV-234
Introduction The HDV genome exists as a negative sense, single-stranded, closed circular RNA. Because of a nucleotide sequence that is 70% self-complementary, the HDV genome forms a partially double stranded RNA structure that is described as rod-like. With a genome of approximately 1700 nucleotides, It has been proposed that HDV may have originated from a class of plant viruses called viroids. Evidence in support of this hypothesis stems from the fact that both HDV and viroids exist as single-stranded, closed circular RNAs that have rod-like structures. Likewise, both HDV and viroids contain RNA sequences that can assume catalytically active structures called ribozymes.
Description The E.Coli derived recombinant protein contains the HDV immunodominant regions, amino acids 1-108aa, 151-209aa.
Method Purified by proprietary chromatographic technique.
Purity Protein is >90% pure as determined by 10% PAGE (Coomassie staining).
Formulation 10mM carbonate buffer pH 10.0, NaCl 100mM and 50% glycerol.
Storage HDV although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.
Specificity Immunoreactive with sera HDV-infected individuals.
Applications Antigen in ELISA and Western blots, excellent antigen for detection of HDV with minimal specificity problems.
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