HTLV-1 p24 | ProSpec

Description

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Quantity

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HTLV-1 p24 Recombinant

	100µg($150)
	500µg($600)
	1000µg($1200)

Ice Packs

Catalogue Number

HIV-003

Introduction

Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes
T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly
IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly
Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
HTLV-1 p24 is usually used for clinical diagnosis and forms both monomer and dimer on
SDS-PAGE gel but the majority of protein is a dimer.

Description

HTLV-1 p24 Recombinant produced in E.Coli covers full length of HTLV-1 p24 and contains 188 amino acids having a molecular size 21kDa.
HTLV-1 p24 is purified by proprietary chromatographic technique.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

HTLV-1 p24 protein solution (1mg/1ml) containing 50mM sodium chloride-phosphorous buffer, pH-7.4.

Storage

HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.