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Catalogue Number
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HSP-020
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Synonyms
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Heat Shock Protein 20, HSP20.
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Introduction
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Hsp20 is a mammalian small heat-shock protein family that is found most copiously in skeletal muscle and heart. The heat-shock proteins seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation. The Hsp20 family is characterized structurally by the presence of a conserved C-terminal domain of about 100 residues and contains a beta-sandwich fold consisting of 8 strands in 2 beta-sheets in a “Greek-key” topology. Hsp20 proteins have a tendency to form dimers, through a disulphide linkage formed by an N-terminal cysteine, low heat stability and a poor chaperoning ability in comparison with other family members.
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Description
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Heat Shock Protein 20 Human Recombinant produced in E.Coli.
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Source
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Escherichia Coli.
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Physical Appearance
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Sterile Filtered White lyophilized (freeze-dried) powder.
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Formulation
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HSP20 lyophilized from 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF and 15mM ?-mercaptoethanol.
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Stability
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HSP20 although stable at 10°C for 2 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Purity
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Greater than 95.0% as determined by SDS-PAGE.
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Immunological Activity
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Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSP20.
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Usage
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ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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| Contact Us |
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Website : www.prospecbio.com Email: info@prospecbio.com |
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