GM-CSF Antibody
Granulocyte Macrophage Colony Stimulating Factor, Mouse Anti-Human

Synonyms:
CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim, MGC131935, MGC138897.

Type:
Mouse Anti Human Monoclonal

Introduction:
GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Clone:
NYRhGMCSF

Ig Subclass:
Mouse IgG

Purification Method:
Ion exchange

Protein concentration:
1mg/ml in PBS (after reconstitution)

Shipping Conditions:
Antibody is shipped lyophilized at ambient temperature.

Storage Procedures:
In lyophilized form, for long periods, store at 4^oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20^oC.

Reconstitution:
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4^oC.

Applications:
Direct ELISA, Western Blot, Immuneprecipitation.

Titer:
By direct ELISA, 1:10,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.