prospec
GLTP Human

GLTP Human

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  • Description
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  • GLTP Human

  • Glycolipid Transfer Protein Human Recombinant
  • PRO-1313
  • Shipped with Ice Packs

Catalogue number

PRO-1313

Synonyms

Glycolipid transfer protein, GLTP.

Introduction

Glycolipid transfer protein (GLTP) accelerates the intermembrane transfer of different glycolipids. GLTP catalyzes the transfer of various glycosphingolipids between membranes however does not catalyze the transfer of phospholipids. GLTP is involved in the intracellular translocation of glucosylceramides. The GLTP protein is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. GLTP is assumed to be a cytoplasmic protein. GLTP is detected in fibroblasts and in various cancer cell lines.

Description

GLTP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-209 a.a.) and having a molecular mass of 26.2kDa.
GLTP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

GLTP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMALLAEH LLKPLPADKQ IETGPFLEAV SHLPPFFDCL GSPVFTPIKA DISGNITKIK AVYDTNPAKF RTLQNILEVE KEMYGAEWPK VGATLALMWL KRGLRFIQVF LQSICDGERD ENHPNLIRVN ATKAYEMALK KYHGWIVQKI FQAALYAAPY KSDFLKALSK GQNVTEEECL EKIRLFLVNY TATIDVIYEM YTQMNAELNY KV.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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