GLRX1 | ProSpec

Description

Our Price

Quantity

Shipping

Glutaredoxin 1 Yeast Recombinant

	10µg($50)
	50µg($130)
	1mg($1500)

Ice Packs

Catalogue Number

ENZ-361

Synonyms

Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1.

Introduction

GLRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. reduces low molecular weight disulfides and proteins. Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GLRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.

Description

Glutaredoxin Saccharamyces cerevisiae Recombinant containing 6x His tag at C-Terminus produced in E.Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear colorless solution.

Formulation

Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide.

Stability

1 week at 2-10°C. For long term store at -20 to -80°C.

Purity

Greater than 90% as determined by SDS-PAGE.

Applications

ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.