FKBPL Human | ProSpec

Description

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Quantity

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FK506 Binding Protein Like Human Recombinant

	1µg($50)
	5µg($130)
	50µg($1100)

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Catalogue Number

ENZ-543

Synonyms

WISP39, DIR1, NG7, FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, FKBPL.

Introduction

FKBPL is related to the immunophilin protein family, which take part in immunoregulation and regular cellular processes involving protein folding and trafficking. FKBPL has an important function in the induced radioresistance and participates in the control of the cell cycle. FKBPL has a role in cellular response to stress. FKBPL interacts with Hsp90, glucocorticoid receptor and dynamitin and is involved in signalling, like other FKBPs.

Description

FKBPL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (1-349 a.a.) and having a molecular mass of 39.2 kDa. The FKBPL is fused to 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

FKBPL Human solution containing 20mM Trsi pH-8, 2mM DTT, 0.1M NaCl & 20% glycerol.

Stability

FKBPL Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

METPPVNTIG EKDTSQPQQE WEKNLRENLD SVIQIRQQPR DPPTETLELE VSPDPASQIL EHTQGAEKLV AELEGDSHKS HGSTSQMPEA LQASDLWYCP DGSFVKKIVI RGHGLDKPKL GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNPEGAA RCYGRALRLL LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG NLEKATADLK KVLAIDPKNR AAQEELGKVV IQGKNQDAGL AQGLRKMFGL EHHHHHH.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.