ENO2 Human | ProSpec

Description

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Quantity

Shipping

Neurone Specific Enolase Human

	5µg($50)
	20µg($130)
	1mg($3600)

Ice Packs

Catalogue Number

ENZ-371

Synonyms

Gamma-enolase, EC 4.2.1.11, 2-phospho-D-glycerate hydro-lyase, Neural enolase, Neuron-specific enolase, NSE, Enolase 2, ENO2.

Introduction

Neuron-specificenolase also caled NSE is a glycolytic isoenzyme which is situated in central and peripheral neurons and neuroendocrine cells. Enolase-2 is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue release Enolase-2 into the blood. Enolase-2 is a useful substance that has been detected in patients with certain tumors, such as neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. ENO2 is 1 of the 3 enolase isoenzymes found in mammals. ENO2 isoenzyme, is found in mature neurons and cells of neuronal origin. An exchange from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

Description

Human Neurone Specific Enolase produced in Human CNS having a molecular mass of 45kDa.

Source

Human CNS.

Physical Appearance

Sterile Filtered clear solution.

Formulation

The protein solution is in 0.01M NaH2PO4 buffer pH 7.4 containing 0.15M NaCl and 0.005M MgSO4.

Stability

Human NSE although stable at 4°C for 1 week, should be stored at
-15°C.

Purity

Greater than 96.0%.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.