Dengue Polyvalent

Description

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Polyvalent Dengue Antigen Recombinant

	100µg($150)
	500µg($600)
	1000µg($1200)

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Catalogue Number

DEN-010

Introduction

Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.

Description

Polyvalent dengue antigen is a 22kDa protein that contains 4 dengue antigen subtypes, produced in E.coli and fused to a 6xHis Tag. The immunoreactive peptide span from the viral envelope to the non-functional region. The polyvalent dengue antigen consists of 25% recombinant antigen from each of the dengue subtypes in their composition. The Polyvalent dengue antigen detects all four dengue subtypes. The sensitivity and specificity could reach approximately 93% and 96% in dengue IgG and IgM ELISA assay.

Method

Purified by proprietary chromatographic technique.

Purity

Protein is >95% pure as determined by 10% PAGE (coomassie staining).

Formulation

(0.79mg/ml) Phosphate buffered saline, pH-7.4.

Storage

Polyvalent Dengue although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.

Applications

Each laboratory should determine an optimum working titer for use in its particular application.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.