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Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
The E.coli derived recombinant 23 kDa protein is genetically engineered peptide which is derived from Dengue Type-2 N-terminus Envelope immunodeterminant regions. This region also contains a common antigen for Dengue type 1, 2 and 3.
Purified by proprietary chromatographic technique.
Protein is >95% pure as determined by 10% PAGE (coomassie staining).
50mM sodium chloride-phosphorous buffer, pH-7.5.
Protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.
Five years frozen. One month in solution at room temperature.
Each laboratory should determine an optimum working titer for use in its particular application.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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