About CNPY / Canopy FGF Signalling Regulator:
Canopy FGF signalling regulator is a plasma protein that is found in a variety of areas of the human body, and it is encoded by the CNPY2 gene. It has low tissue specificity but there is a high consistency between the antibody staining of CNPY and the RNA data expression data. Something to watch out for is that it does target protein from more than one gene, when used in immunohistochemistry. CNPY has an enhanced cell type, otherwise known as Extravillous trophoblasts. The protein function of CNPY is a positive regulator of outgrowth by being able to stabilize the myosin regulatory light chain (MRLC). As a result, it helps to prevent any MIR-mediated MRLC and prevent any of the subsequent proteasomal degradation of the protein function.
CNPY Structure
CNPY is found usually in an intracellular location, but its subcellular location is localized to the cytosol. There is evidence of the cell at protein level, as well as it having low cell line specificity when it comes to RNA cell specificity. In the brain, CNPY is detected in all regions, with the more found in the cerebral cortex. There is low region specificity and low tissue specificity in the brain atlas too.
Canopy FGF Signaling Regulator Function
CNPY is an indicator or marker of two types of cancer, in renal cancer and in pancreatic cancer. Although it is a marker for these two types of cancer, it can be found or detected in all types of cancer. For renal cancer, it is an unfavourable marker, and for pancreatic cancer it is a favourable marker.