CD80 Antibody
B7-1 (CD80), Rat Anti-Mouse

Synonyms:
LAB7, CD28LG, CD28LG1, CD28LG1, B71

Type:
Rat Anti Mouse Monoclonal

Introduction:
The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor.

Clone:
mB7-1

Immunogen:
Purified mouse LPS-activated B cells

Purification Method:
Ion exchange column

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4^oC. After reconstitution, if not intended for use within a month, aliquot and store at -20^oC.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4^oC.

Antibody Properties:
Blocking and staining antibody. For staining, use 10 µl/10⁶ cells. Titer for blocking T cell activation should be determined by the investigator.

Available Conjugates:
This antibody is only available as purified antibody.

Usage:
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.