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Protein Catalog >> CD Antigens >> CD Antigens >> CD4 Human (203-317)
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Description
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CD-4 (203-317 a.a.) Human Recombinant
 
Catalogue Number CYT-316
Synonyms gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.
Introduction CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
Description CD-4 Human Recombinant His Tag protein encoding 203-317 amino acids.
Source Escherichia Coli.
Physical Appearance Sterile lyophilized powder.
Formulation Each mg contains 1X PBS, 0.1% SDS and 1mM DTT.
Stability Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months.
Please avoid freeze-thaw cycles.
Applications • Protein Assay.
• Antibody Production.
• Western Blotting.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Solubility

It is recommended to reconstitute the lyophilized CD-4 (203-317)in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

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