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Catalogue Number
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PRO-534
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Synonyms
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PEBP2B, polyomavirus enhancer binding protein b, PEA2, CBF-beta.
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Introduction
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CBFB beta subunit is a heterodimeric core-binding transcription factor that is part of the PEBP2/CBF transcription factor family which controls a host of genes particulary to hematopoiesis and osteogenesis. CBFB is a non-DNA binding regulatory subunit which increases DNA binding by alpha subunit.
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Description
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CBFB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (1-202 a.a.) and having a molecular mass of 23.6 kDa. The CBFB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
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Source
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Escherichia Coli.
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Physical Appearence
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Sterile filtered colorless solution.
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Formulation
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0.5mg/ml solution containing 20mM MES pH-6, 0.1mM PMSF & 10% glycerol.
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Stability
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CBFB Human although stable at 4C for 1 week, should be stored
below -18C. Please prevent freeze thaw cycles.
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Purity
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Greater than 85.0% as determined by SDS-PAGE.
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Amino Acid Sequence
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MGSSHHHHHH SSGLVPRGSH MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFP
ASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSH
REEMEVRVSQ LLAVTGKKTT RP.
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Usage
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ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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Website : www.prospecbio.com
Email: info@prospecbio.com |
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