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Catalogue Number
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PRO-460
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Synonyms
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B-cell lymphoma 6 protein, BCL-6, Zinc finger protein 51, LAZ-3 protein, BCL-5, Zinc finger and BTB domain-containing protein 27, BCL6, BCL5, LAZ3, ZBTB27, ZNF51, BCL6A.
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Introduction
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Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease.
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Description
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Bcl-6 Human Recombinant (aa 1-150) expressed in E.coli, shows a 43 kDa band on SDS-PAGE (Icluding GST tag).
The Bcl-6 is purified by proprietary chromatographic techniques.
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Source
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Escherichia Coli.
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Physical Appearance
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Sterile Filtered clear solution.
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Formulation
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Bcl-6 protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
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Stability
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Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
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Applications
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• ELISA
• Inhibition Assays
• Western Blotting.
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Usage
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Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Related Products
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Postal Address: PO Box 4157,
Ness-Ziona, 74140 Israel
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Website : www.prospecbio.com
Email: info@prospecbio.com |
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