Acrp30 Mouse, His
Adiponectin Mouse Recombinant, His Tag

Synonyms:
Acrp30, AdipoQ, GBP-28, APM-1, ACDC.

Introduction:
Adiponectin is an adipocyte specific secreted protein that circulates in the plasma. It is induced during adipocyte differentiation and its secretion is stimulated by insulin. Mouse adiponectin shares about 83% amino acid identity with that human. Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Adiponectin is reduced in obese humans, and decreased level is associated with insulin resistance and hyperinsulinemia.

Description:
The Acrp30 Mouse is created as a recombinant protein with N-terminal fusion of His Tag.
The Adiponectin His-Tagged Fusion Protein, produced in E. coli, is a 27 kDa protein containing 251 amino acid residues of the Acrp30 Mouse, 18-247 amino acids.

Source:
Escherichia Coli.

Formulation:
Acrp30 Mouse is a sterile filtered liquid formulation containing 20mM Tris pH-8, 1mM DTT and 10% Glycerol.

Stability:
Store Acrp30 Mouse at -20°C. Can be stored at 4°C for a limited period of time of 7 days.

Purity:
Acrp30 Mouse purity is greater than 90% as determined by SDS-PAGE analyzed.

Amino Acid Sequence:
MGSSHHHHHH SSGLVPRGSH MEDDVTTTEE LAPALVPPPK GTCAGWMAGI
PGHPGHNGTP GRDGRDGTPG EKGEKGDAGL LGPKGETGDV
GMTGAEGPRG FPGTPGRKGE PGEAAYVYRS AFSVGLETRV TVPNVPIRFT
KIFYNQQNHY DGSTGKFYCN IPGLYYFSYH ITVYMKDVKV SLFKKDKAVL
FTYDQYQEKN VDQASGSVLL HLEVGDQVWL QVYGDGDHNG
LYADNVNDST FTGFLLYHDT N.

References:
Yokota. T. et al. (2000) Blood. 96:1723
Yamauchi T. et al (2002) Nature Medicine.8(11):
1288-1295
Lu M. et al (2007) Mol Endocrinol.59(2):207-16.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.