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Protein Catalog >> Recombinant Proteins >> Annexin >> ANXA9 Human
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Description
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Annexin A9 Human Recombinant
Ice Packs
Catalogue Number PRO-450
Synonyms Annexin A9, Annexin-9, Annexin-31, Annexin XXXI, Pemphaxin, ANXA9, ANX31.
Introduction The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin 31 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin 31 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
Description ANXA-9 Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids (1-338) and having a total molecular mass of 38.9 kDa.
ANXA9 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation Annexin-9 at a concentration of 0.1mg containing 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
Stability Annexin-9 although stable at 4°C for 1 week, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Applications • ELISA
• MS
• Western Blotting.
Purity Greater than 95.0% as determined by SDS-PAGE.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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