AMD1 Human
S-Adenosylmethionine Decarboxylase Human Recombinant

Synonyms:
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SamDC, AMD, ADOMETDC, FLJ26964, DKFZp313L1234, AMD1.

Introduction:
AMD1 catalyzes the removal of the carboxylate group of S-adenosylmethionine in the polyamine biosynthesis pathway. Adenosylmethionine decarboxylase is an enzyme which catalyzes the conversion of S-Adenosyl methionineto S-adenosyl-5'-3-methylpropylamine.
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.

Description:
S-Adenosylmethionine Decarboxylase Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 334 and having a total molecular mass of 38.3 kda. AMD1 contains T7 tag at N-terminus.
AMD-1 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Formulation:
AdoMetDC at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN₃.

Stability:
S-Adenosylmethionine Decarboxylase although stable at 14°C for 1 week, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Applications:
• ELISA
• MS
• Inhibition Assays
• Western Blottin

Purity:
Greater than 95.0% as determined by SDS-PAGE.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.