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Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2.
Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Acetyl-Coenzyme A acetyltransferase 2 produced Human Recombinant in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-397 and having a total molecular mass of 41.3 kda. ACAT2 contains T7 tag at N-terminus.
ACAT-2 is purified by proprietary chromatographic techniques.
Escherichia Coli.
Sterile Filtered clear solution.
Acetyl-CoA acetyltransferase cytosolic in 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
ACAT2 although stable at 14°C for 1 week, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
• ELISA
• MS
• Inhibition Assays
• Western Blotting
Greater than 95.0% as determined by SDS-PAGE.
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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